Maintenance of redox homeostasis by hypoxia-inducible factors
نویسندگان
چکیده
منابع مشابه
Maintenance of redox homeostasis by hypoxia-inducible factors
Oxidative phosphorylation enables cells to generate the large amounts of ATP required for development and maintenance of multicellular organisms. However, under conditions of reduced O2 availability, electron transport becomes less efficient, leading to increased generation of superoxide anions. Hypoxia-inducible factors switch cells from oxidative to glycolytic metabolism, to reduce mitochondr...
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ژورنال
عنوان ژورنال: Redox Biology
سال: 2017
ISSN: 2213-2317
DOI: 10.1016/j.redox.2017.05.022